Speed, reach, and flexibility define the Nikon AF-S 120-300mm f/2.8E FL ED SR VR; an F-mount telephoto zoom characterized by an advanced optical design, quick focusing performance, and a bright f/2.8 constant maximum aperture. Fluorite, short-wavelength refractive (SR), and extra-low dispersion (ED) glass is used throughout the optical layout to effectively suppress a variety of aberrations for improved clarity, sharpness, and color accuracy throughout the zoom range. ARNEO and Nano Crystal Coats, as well as a Super Integrated Coating, have been applied, too, to suppress flare, ghosting, and surface reflections for improved contrast and color fidelity.

Balancing the optical merits, this 120-300mm is also characterized by its inclusion of a Vibration Reduction image stabilization system that compensates for camera shake to enable sharper handheld shooting. A Silent Wave Motor also benefits producing sharp imagery and affords quick and quiet autofocus performance along with full-time manual focus override. Additionally, a rotating tripod collar is featured to assist working with a support system and this lens utilizes an electromagnetic diaphragm to ensure consistent exposure stability when shooting at fast continuous speeds.